Enrique Chang, global chief investment officer at Janus Henderson Group, will retire effective April 1.
Following his departure, Janus Henderson will "consider the management framework of the investments team," a spokeswoman said in an email.
During that process, Alex Crooke and George Maris, co-heads of equities, and Jim Cielinski, global head of fixed income, will work together with the manager's investment leadership team to lead the firm's investment activity, the spokeswoman said.
The announcement comes after last week's news that Ali Dibadj will succeed Dick Weil as CEO of Janus Henderson. Mr. Weil is retiring at the end of March and Mr. Dibadj will start no later than June 27, a news release said on March 23.
Roger Thompson, chief financial officer, will serve as interim CEO until Mr. Dibadj's arrival.
On Feb. 3, Janus Henderson announced plans to sell quantitative equities subsidiary Intech Investment Management in a management-led buyout. Two days earlier, Trian Partners, which owns 16.7% of Janus Henderson shares, gained two board seats at the manager. Although Trian's plans for Janus Henderson have yet to be determined, co-founder Ed Garden spoke recently about the need for industry consolidation.
Mr. Chang originally joined predecessor firm Janus Capital Group in 2013 as chief investment officer of equities and asset allocation at Janus Capital Group.
Janus Henderson had $432 billion in assets under management as of Dec. 31.