University of Chicago's endowment returned -8.8% for the fiscal year ended June 30.
Endowment assets fell over the year to $10.3 billion from $11.6 billion the year before, according to an announcement on the university's website.
For the 10 and 20 years ended June 30, the endowment returned an annualized 7.6% and 8.7%, respectively.
The Nov. 18 announcement did not say whether the returns were gross or net of fees and did not provide benchmark information or returns by asset class.
The endowment had returned a net 37.6% for the fiscal year ended June 30, 2021.
For the most recent fiscal year, the university's announcement cited poor equity and fixed-income returns for the overall negative performance.