Alvaro Aguirre-Simunovic, natural resources portfolio manager at Harvard Management Co., is resigning, effective Oct. 9, a spokeswoman confirmed.
It could not be learned where he is going.
Satu Parikh, head of commodities at HMC, will oversee the natural resources portfolio while HMC searches for a permanent replacement.
Mr. Aguirre-Simunovic's departure follows that of his boss, Andrew Wiltshire, the head of alternative investments, who on Sept. 11 announced his intention to retire later this year.
Mr. Aguirre-Simunovic was one of Harvard's highest-paid money managers. In 2013, he earned $9.6 million, a 44.7% bump up from the prior year. By comparison, Jane Mendillo, HMC's former president and CEO, also made $9.6 million during 2013, up 99% from the year before. Mr. Wiltshire, his boss, earned $8.5 million, up 7.6% from what he earned in 2012.
HMC oversees Cambridge, Mass.-based Harvard University's $37.6 billion endowment.
The endowment posted a 5.8% gain for the fiscal year ended June 30.